This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the sp…
Flavonoids are abundant secondary metabolites found in plants and fungi that have various roles in these organisms, including pigmentation, cell signalling, plant defence and inter-organism communication. Due to their abundance in nature, flavonoids are also important components of the human diet, and the last four decades have seen an intense study focused on the structure characterization of …
The third edition of this indispensable book in radio interferometry provides extensive updates to the second edition, including results and technical advances from the past decade; discussion of arrays that now span the full range of the radio part of the electromagnetic spectrum observable from the ground, 10 MHz to 1 THz; an analysis of factors that affect array speed; and an expanded discus…
This book is open access under a CC BY 4.0 license. This book examines how China can increase the share of natural gas in its energy system. China’s energy strategy has global ramifications and impact, and central to this strategy is the country’s transition from coal to gas. The book presents the culmination of a two-year collaboration between the Development Research Center of the State C…
This open access book offers comprehensive coverage on Ordered Fuzzy Numbers, providing readers with both the basic information and the necessary expertise to use them in a variety of real-world applications. The respective chapters, written by leading researchers, discuss the main techniques and applications, together with the advantages and shortcomings of these tools in comparison to other f…
This book studies the foundations of quantum theory through its relationship to classical physics. This idea goes back to the Copenhagen Interpretation (in the original version due to Bohr and Heisenberg), which the author relates to the mathematical formalism of operator algebras originally created by von Neumann. The book therefore includes comprehensive appendices on functional analysis and …
"Scientists deserve public recognition. The ways that they are depicted, however, are severely limited in physical and personal traits, helping to establish and enhance stereotypes under the general title of ‘scientist’. These stereotypes range from the arrogant researcher who wants to rule the world, to the lab coat wearing ‘nerdy’ genius, but all generally fall to an extreme view of a…
"The digital era has brought about huge transformations in the map itself, which to date have been largely conceptualised in spatial terms. Novel objects, forms, processes and approaches have emerged and pose new, pressing questions about the temporality of digital maps and contemporary mapping practices: in spite of its implicit spatiality, digital mapping is strongly grounded in time. This co…
This book aims to inspire decision makers and practitioners to change their approach to climate planning in the tropics through the application of modern technologies for characterizing local climate and tracking vulnerability and risk, and using decision-making tools. Drawing on 16 case studies conducted mainly in the Caribbean, Central America, Western and Eastern Africa, and South East Asia …
This book aims to provide case studies and a general view of the main processes involved in the ecosystem shifts occurring in the high mountains, and to analyse the implications for nature conservation. Although case studies from the Pyrenees are preponderant, conclusions are aimed at any mountain range surrounded by highly populated lowland areas. The chapters give emphasis to approaches from …
Kita menyadari bahwa negara kita merupakan negara bahari yang terdiriatas lebih dari 17.000 pulau dengan garis pantai yang membentang sepanjang lebih dari 99.000 km. Secara geologi Indonesia memiliki banyakpatahan gempa karena dikelilingi oleh tiga lempeng tektonik, yaitu lempengIndo-Australia, lempeng Eurasia, dan lempeng Pasifik yang pertemuannya berada di laut. Di samping itu, wilayah Indone…
This easy-to-read book introduces the basics of solving partial differential equations by means of finite difference methods. Unlike many of the traditional academic works on the topic, this book was written for practitioners. Accordingly, it especially addresses: the construction of finite difference schemes, formulation and implementation of algorithms, verification of implementations, analys…
The Gulf of Mexico is an open and dynamic marine ecosystem rich in natural resources but heavily impacted by human activities, including agricultural, industrial, commercial and coastal development. Nutrients and pollutants from coastal communities and dozens of rivers flow into the Gulf, including material from the Mississippi River watershed, which drains over one third of continental United …
This open access book, inspired by the ICME 13 Thematic Afternoon on “European Didactic Traditions”, consists of 17 chapters, in which educators from the Netherlands reflect on the teaching and learning of mathematics in their country and the role of the Dutch domain-specific instruction theory of Realistic Mathematics Education. Written by mathematics teachers, mathematics teacher educator…
This open access book is the first major publication on the topic of “Interdisciplinary Mathematics Education” and arose from the work of the first International Topic Study Group of the same name at the ICME-13 conference in Hamburg in 2016. It offers extensive theoretical insights, empirical research, and practitioner accounts of interdisciplinary mathematics work in STEM and beyond (e.g.…
Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médecine et Recherche has brought together experts f…
This book facilitates an integrative understanding of the development, genetics and evolution of butterfly wing patterns. To develop a deep and realistic understanding of the diversity and evolution of butterfly wing patterns, it is essential and necessary to approach the problem from various kinds of key research fields such as “evo-devo,” “eco-devo,” ”developmental genetics,” “e…
With this graduate-level primer, the principles of the standard model of particle physics receive a particular skillful, personal and enduring exposition by one of the great contributors to the field. In 2013 the late Prof. Altarelli wrote: The discovery of the Higgs boson and the non-observation of new particles or exotic phenomena have made a big step towards completing the experimental conf…
Migrations and population dynamics are considered very problematic topics in the fields of ancient studies. Recent scholarship in (pre)historical population has generated new impulses by using scientific approaches using radiogenic and stable isotopes, and palaeogenetics, as well as computer simulation. As a result, the state of migration research has undergone rapid change. Several research gr…
This book provides a unique overview of the impacts of railways on biodiversity, integrating the existing knowledge on the ecological effects of railways on wildlife, identifying major knowledge gaps and research directions and presenting the emerging field of railway ecology. The book is divided into two major parts: Part one offers a general review of the major conceptual and theoretical p…